Gaining in Years But Losing in Muscle
Friday, August 24, 2012, 03:00 PM
Moby-B-Complex, Room 211

The Department of Health & Exercise Science presents a seminar by Russell T. Hepple, Ph.D., from the Department of Critical Care Medicine, McGill University Health Centre & the Department of Kinesiology, McGill University, Quebec, Canada: Current Perspectives on the Causes of Aging-Related Muscle Atrophy Sarcopenia refers to the loss of muscle mass with aging and is a major cause of physical frailty in individuals =75 y of age.

Amongst the most frequently implicated causes of sarcopenia are defects in mitochondrial function. In contrast to this view, our recent studies have revealed that the extent of mitochondrial dysfunction has likely been exaggerated in previous studies owing to high reliance on methods that do not preserve the in vivo mitochondrial network.

Our studies also show that the extent of mitochondrial dysfunction between muscles does not vary in a way that predicts their atrophy susceptibility, raising important questions about the causes and implications of mitochondrial alterations for sarcopenia.

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Event Contact: Chris Bell can be reached at (970) 491-7522

Sponsored by the Department of Health and Exercise Science.